The historic centre stretches along a tufaceous strip overlooking the Via Cassia, amidst woods with oaks, turkey oaks, chestnuts and vast hazel groves, on the southern slopes of the Cimini mountains. The town is famous for its water (effective against stomach and intestinal disorders), which was praised by Petrarch when he stayed there in 1337, the guest of Orso Anguillara. In the Romanesque church of San Francesco is the magnificent sepulchre of Francesco and Nicola Anguillara, twin brothers who died in 1406 and 1408. This Gothic-style work has been attributed to Paolo Romano. The cathedral of San Giovanni Battista (built in the sixteenth century, but reconstructed in the nineteenth century) safeguards a Renaissance tabernacle, a sixteenth-century wooden crucifix and a historic nineteenth-century organ. At the neo-classic church of Santa Maria (1867), we can admire the statue of Our Lady of Grace (1808), an excellent tavola dating to the twelfth-thirteenth century depicting Christ Benedictory, a fifteenth-century tabernacle and a triptych (fifteenth-sixteenth century) with St. Terenziano, St. Rocco and St. Sebastian being venerated by one of the faithful.

The church of Santa Maria del Piano has an elegant wooden ceiling and several frescoes attributed to the Zuccari brothers.